Atherosclerotic Plaque : Role of Activated Macrophages and Inflammatory Cytokines Increased Expression of Membrane Type 3-Matrix Metalloproteinase in Human
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Pinky V. Tripathi, Stefan Jovinge, Douglas J. Wilkin, Kamlesh Asotra, Prediman K. Shah and Hiroyasu Uzui, Alice Harpf, Ming Liu, Terence M. Doherty, Arun Shukla, Ning-Ning Chai, Atherosclerotic Plaque : Role of Activated Macrophages and Inflammatory Cytokines Increased Expression of Membrane Type 3-Matrix Metalloproteinase in Human Print ISSN: 0009-7322. Online ISSN: 1524-4539 Copyright © 2002 American Heart Association, Inc. All rights reserved. is published by the American Heart Association, 7272 Greenville Avenue, Dallas, TX 75231 Circulation doi: 10.1161/01.CIR.0000041433.94868.12 2002;106:3024-3030; originally published online November 18, 2002; Circulation. http://circ.ahajournals.org/content/106/24/3024 World Wide Web at: The online version of this article, along with updated information and services, is located on the
منابع مشابه
Increased expression of membrane type 3-matrix metalloproteinase in human atherosclerotic plaque: role of activated macrophages and inflammatory cytokines.
BACKGROUND Matrix metalloproteinases (MMPs) are thought to play a prominent role in atherogenesis and destabilization of plaque. Pericellularly localized membrane-type (MT)-MMPs activate secreted MMPs. We investigated the hypothesis that MT3-MMP is expressed in human atherosclerotic plaques and is regulated by locally produced inflammatory cytokines and oxidized low-density lipoprotein (Ox-LDL)...
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تاریخ انتشار 2002